PsilodexMedication × psilocybin
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Supplements and over the counter
Brand names
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Reviewed 2026-10-02

Alpha-lipoic acid (ALA)

psilodex.org/m/alpha-lipoic-acid · data v2026.10.02

Clinical contraindication
None listed
No clinical contraindication identified.
Best available evidence
Case reports
Half-life
Not recorded
Named in state rules?
CONot named
ORNot named
NMPending
Cite asPsilodex: alpha-lipoic-acid · v2026.10.02

Clinical data and state rules are separate facts. Both are shown; neither is a decision.

01 Interaction with psilocybin

CR

Trials show little glucose-lowering effect, but ALA is a recognized trigger of insulin autoimmune syndrome, causing recurrent hypoglycemia in genetically susceptible people. Relevant where meals are reduced around a session. Not to be confused with alpha-linolenic acid. No psilocybin-specific data.

Human data with psilocybin
Case reports or surveys only
Evidence types on this record
CRCase reports or online surveys

02 Pharmacology relevant to psilocybin

1 listed · counted on reports
Hypoglycemia risk
Can cause low blood sugar, especially if meals are missed or delayed. Sources [2][3]

03 State rules

Plain-language summary · official text governs
CO4 CCR 755-1
Not named

No provision names this medication or its class.

Colorado · checked 2026-09-30
OROAR 333-333
Not named

No provision names this medication or its class.

Oregon · checked 2026-09-30
NM7.35.3 NMAC (proposed)
Pending

New Mexico's clinical rules (proposed 7.35.3 NMAC) are not final. No provision naming this medication has been found.

New Mexico · checked 2026-10-02

04 Conditions to ask about

None linked

No condition named in state rules is linked to this medication.

05 Sources

3
  1. NIH National Center for Complementary and Integrative Health fact sheet (per-entry link)
  2. Vallianou NG, Kounatidis DC, Dalamaga M, et al. Alpha-lipoic acid as a trigger of insulin autoimmune syndrome: current evidence, a case-based approach, diagnostic pitfalls, and practical management. Metabol Open 2026;31:100491. — ALA-associated insulin autoimmune syndrome review
  3. Viti L, Tartaglione L, Rizzi A, et al. A case of Hirata syndrome in pregnancy induced by alpha-lipoic acid: diagnosis and management. AACE Endocrinol Diabetes 2025;12(2):84-88. — case report

Record history

  • v2026.10.02First published.
  • 2026-10-02Last reviewed against its sources.

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Before you startTerms v2026-10-01

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