Amanita muscaria products / muscimol gummies

Clinical contraindication: None listed; No clinical contraindication identified.
Best available evidence: Mechanism only
Half-life: Not recorded

Named in state rules?

CONot named

ORNot named

NMPending

Cite asPsilodex: amanita-muscaria-muscimol · v2026.10.02

Clinical data and state rules are separate facts. Both are shown; neither is a decision.

01 Interaction with psilocybin

Muscimol is a GABA-A agonist and ibotenic acid a glutamate agonist; poisoning series describe CNS depression, excitation and GI upset. Product content is unpredictable, and some gummies labeled Amanita contained undisclosed psilocin or other tryptamines.

Human data with psilocybin: None known: no published human data with psilocybin

Evidence types on this record

ThMechanism only (theoretical)

02 Pharmacology relevant to psilocybin

1 listed · counted on reports

Sedating or CNS depressant: Slows the central nervous system: drowsiness, slower reactions and impaired coordination, and slowed breathing at high doses. Effects add with other sedating substances. Sources [2]

03 State rules

Plain-language summary · official text governs

CO4 CCR 755-1

Not named

No provision names this medication or its class.

Colorado · checked 2026-09-30

OROAR 333-333

Not named

No provision names this medication or its class.

Oregon · checked 2026-09-30

NM7.35.3 NMAC (proposed)

Pending

New Mexico's clinical rules (proposed 7.35.3 NMAC) are not final. No provision naming this medication has been found.

New Mexico · checked 2026-09-30

04 Conditions to ask about

None linked

No condition named in state rules is linked to this medication.

05 Sources

US FDA consumer or public-health page (per-entry link) — Dec 2024: A. muscaria, muscimol, ibotenic acid not authorized in food; not GRAS
Moss MJ, Hendrickson RG. Toxicity of muscimol and ibotenic acid containing mushrooms reported to a regional poison control center from 2002-2016. Clin Toxicol (Phila) 2019;57(2):99-103. — poison center series: CNS depression and excitation, GI symptoms
Correia MS, Gonzaga MJ, Temple C, Gerona RR. Quantitative analysis of recreational psychoactive mushroom gummies in Portland, Oregon. Clin Toxicol (Phila) 2025;63(4):261-266. — Amanita-labeled gummies contained psilocin/tryptamines, no muscimol detected

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