Budesonide / glycopyrrolate / formoterol

psilodex.org/m/budesonide-glycopyrrolate-formoterol · data v2026.10.02

Clinical contraindication: None listed; No clinical contraindication identified.
Best available evidence: Standard practice
Half-life: Not recorded

Named in state rules?

CONot named

ORNot named

NMPending

Cite asPsilodex: budesonide-glycopyrrolate-formoterol · v2026.10.02

Clinical data and state rules are separate facts. Both are shown; neither is a decision.

01 Interaction with psilocybin

Inhaled triple therapy. Formoterol can raise pulse and blood pressure in some people, adding to psilocybin's cardiovascular rise; glycopyrrolate is an anticholinergic (labeled cautions for narrow-angle glaucoma and urinary retention).

Human data with psilocybin: None known: no published human data with psilocybin

Evidence types on this record

PrStandard practice; no psilocybin-specific data

02 Pharmacology relevant to psilocybin

2 listed · counted on reports

Raises blood pressure or heart rate: Raises blood pressure or heart rate. Psilocybin raises both for several hours, so the effects can add. Sources [1]
Anticholinergic: Blocks acetylcholine. Can cause a fast heart rate, dry mouth, reduced sweating and heat intolerance, and confusion, more so at high doses or in combination. Sources [1]

03 State rules

Plain-language summary · official text governs

CO4 CCR 755-1

Not named

No provision names this medication or its class.

Colorado · checked 2026-09-30

OROAR 333-333

Not named

No provision names this medication or its class.

Oregon · checked 2026-09-30

NM7.35.3 NMAC (proposed)

Pending

New Mexico's clinical rules (proposed 7.35.3 NMAC) are not final. No provision naming this medication has been found.

New Mexico · checked 2026-10-02

04 Conditions to ask about

Screening items in state rules

This medication is usually taken for a condition. State rules screen for some conditions directly, so the medication is a prompt to ask about them. Confirm with the participant; never assume a condition from the medication.

Severe COPDCO 2.5(A)(2)

05 Sources

Breztri Aerosphere (Budesonide, Glycopyrrolate, and Formoterol Fumarate) Aerosol, Metered · FDA label (DailyMed) — Cardiovascular effects (pulse, BP); 5.15 glaucoma; 5.16 urinary retention

Record history

v2026.10.02First published.
2026-10-02Last reviewed against its sources.

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