PsilodexMedication × psilocybin
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Supplements and over the counter
Brand names
—
Reviewed 2026-10-02

DMAA / DMHA stimulants

psilodex.org/m/dmaa-dmha-stimulants · data v2026.10.02

Clinical contraindication
None listed
No clinical contraindication identified.
Best available evidence
Mechanism only
Half-life
Not recorded
Named in state rules?
CONot named
ORNot named
NMPending
Cite asPsilodex: dmaa-dmha-stimulants · v2026.10.02

Clinical data and state rules are separate facts. Both are shown; neither is a decision.

01 Interaction with psilocybin

Th

FDA states DMAA narrows blood vessels, raises blood pressure, and is linked to arrhythmia, heart attack and seizures; DMHA (octodrine) is an unsafe additive. Supplement analyses found octodrine above former pharmaceutical doses. Effects could add to psilocybin's blood pressure and heart rate rise.

Human data with psilocybin
None known: no published human data with psilocybin
Evidence types on this record
ThMechanism only (theoretical)

02 Pharmacology relevant to psilocybin

2 listed · counted on reports
Raises blood pressure or heart rate
Raises blood pressure or heart rate. Psilocybin raises both for several hours, so the effects can add. Sources [1]
Lowers seizure threshold or carries seizure risk
Makes a seizure more likely, or has been linked to seizures. Sources [1]

03 State rules

Plain-language summary · official text governs
CO4 CCR 755-1
Not named

No provision names this medication or its class.

Colorado · checked 2026-09-30
OROAR 333-333
Not named

No provision names this medication or its class.

Oregon · checked 2026-09-30
NM7.35.3 NMAC (proposed)
Pending

New Mexico's clinical rules (proposed 7.35.3 NMAC) are not final. No provision naming this medication has been found.

New Mexico · checked 2026-10-02

04 Conditions to ask about

None linked

No condition named in state rules is linked to this medication.

05 Sources

3
  1. US FDA consumer or public-health page (per-entry link)
  2. US FDA consumer or public-health page (per-entry link)
  3. Cohen PA, Travis JC, Keizers PHJ, Deuster P, Venhuis BJ. Four experimental stimulants found in sports and weight loss supplements: 2-amino-6-methylheptane (octodrine), 1,4-dimethylamylamine (1,4-DMAA), 1,3-dimethylamylamine (1,3-DMAA) and 1,3-dimethylbutylamine (1,3-DMBA). Clin Toxicol (Phila) 2018;56(6):421-426. — octodrine and DMAA analogs found in US supplements

Record history

  • v2026.10.02First published.
  • 2026-10-02Last reviewed against its sources.

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Before you startTerms v2026-10-01

What Psilodex is, and isn't.

  1. 01Psilodex summarizes published evidence and public state rules. It does not decide whether you can safely use psilocybin or take part in services, and it is not medical advice.
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